New guidelines on primary PCI for patients with STEMI: changing insights

The 2013 recommendation was Class III (Harm), indicating that PCI should not be performed in a non-infarct artery at the time of primary PCI in patients with STEMI who are haemodynamically stable (Level of Evidence B). The new recommendation of 2015 is now Class IIb, demonstrating that PCI of a non-infarct artery may be considered in selected patients with STEMI and multi-vessel disease who are haemodynamically stable, either at the time of primary PCI or as a planned staged procedure (Level of Evidence B-R). It was commented that the 2015 recommendation changed from Class III (Harm) to Class IIb and expanded the time frame in which multi-vessel PCI could be performed.